Protein Details: Glycine receptor subunit alpha-1

Protein ID

ICDB_Pro_0420

Protein Name

Glycine receptor subunit alpha-1

Gene Name

GLRA1

Organism

Homo sapiens (Human)

Length

457 amino acids

AlphaFoldDB

AF-P23415-F1-model_v4.pdb

Function

Sequence

MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ

PDB Structures

1MOT 1VRY 2M6B 2M6I 4X5T 8DN2 8DN4 8DN5

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

220;222;230-235;243;289

Disease

Hyperekplexia 1 and Hyperekplexia